Dialysis is indicated in CKD when GFR falls below which threshold in general?

• A. 15 mL/min
• B. 10 mL/min
• C. 25 mL/min
• D. 5 mL/min

Answer: (B)

Dialysis is considered when kidney function declines to a level where waste products, acid, and excess fluid can no longer be managed, and symptoms or dangerous metabolic disturbances begin to occur. In practice, the tipping point for initiating dialysis is around very low GFR, where the body can’t maintain homeostasis on its own. Around 10 mL/min of GFR represents a practical cutoff where conservative management becomes unlikely to control uremia and its complications, so starting dialysis is generally indicated. The other options don’t fit as well: 25 mL/min is still functioning fairly well and would usually not require dialysis yet; 15 mL/min is a common reference point but is more of a discussion threshold than a guaranteed indication; 5 mL/min would typically reflect an urgent or crisis situation, not a general indication. In summary, at about 10 mL/min, dialysis becomes the appropriate general option to prevent progression of uremic complications.