Hepatitis D virus infection requires concomitant infection with which virus?

Study for the PANCE Precision Exam. Improve with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Hepatitis D virus infection requires concomitant infection with which virus?

Explanation:
Hepatitis D is a defective RNA virus that cannot form its own outer envelope. It relies on the hepatitis B virus to provide the surface antigen (HBsAg) that it uses to assemble infectious virions and enter liver cells. Because of this dependency, HDV can only infect people who have Hepatitis B infection, either at the same time or as a superinfection on chronic HBV. Vaccination against HBV or clearance of HBV protects against HDV, since without HBV there’s no envelope for HDV to use. Hepatitis A or C do not supply this envelope, and HDV is not able to act independently.

Hepatitis D is a defective RNA virus that cannot form its own outer envelope. It relies on the hepatitis B virus to provide the surface antigen (HBsAg) that it uses to assemble infectious virions and enter liver cells. Because of this dependency, HDV can only infect people who have Hepatitis B infection, either at the same time or as a superinfection on chronic HBV. Vaccination against HBV or clearance of HBV protects against HDV, since without HBV there’s no envelope for HDV to use. Hepatitis A or C do not supply this envelope, and HDV is not able to act independently.

Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy