Hyperthyroidism systemic features

• A. Hypertension, edema, fatigue, hyperkalemia
• B. Tachycardia, weight loss, heat intolerance, menstrual irregularities
• C. Weight gain, cold intolerance, bradycardia, constipation
• D. Hypotension, hypothermia, dry skin, myxedema

Answer: (B)

Hyperthyroidism drives a hypermetabolic state, which shows up as systemic signs driven by increased energy expenditure and heightened sympathetic activity. The heart speeds up, producing tachycardia as the body circulates more quickly to meet higher metabolic demands. Weight loss occurs because of accelerated catabolism despite appetite changes. Heat intolerance comes from excess heat production—people feel warm even in normal conditions. Menstrual irregularities arise because thyroid hormones influence the hypothalamic–pituitary–ovarian axis and related sex hormone binding and regulation, often leading to lighter or irregular menses.

These features contrast with the other descriptions that align more with hypothyroidism or non-typical presentations, such as weight gain with cold intolerance and bradycardia, or dry skin and myxedema.