In gout, which type of crystals are deposited in synovial fluid?

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Multiple Choice

In gout, which type of crystals are deposited in synovial fluid?

Explanation:
Gout results from hyperuricemia causing monosodium urate crystals to deposit in the joint space and synovial fluid. These crystals are needle-shaped and exhibit negative birefringence under polarized light, meaning they appear yellow when aligned parallel to the slow axis and blue when perpendicular. This pattern distinguishes them from calcium pyrophosphate crystals seen in pseudogout, which are rhomboid-shaped and positively birefringent. Hydroxyapatite and cholesterol crystals are associated with other joint conditions and don’t match the classic gout crystal morphology. So, the crystals deposited in synovial fluid in gout are monosodium urate crystals.

Gout results from hyperuricemia causing monosodium urate crystals to deposit in the joint space and synovial fluid. These crystals are needle-shaped and exhibit negative birefringence under polarized light, meaning they appear yellow when aligned parallel to the slow axis and blue when perpendicular. This pattern distinguishes them from calcium pyrophosphate crystals seen in pseudogout, which are rhomboid-shaped and positively birefringent. Hydroxyapatite and cholesterol crystals are associated with other joint conditions and don’t match the classic gout crystal morphology. So, the crystals deposited in synovial fluid in gout are monosodium urate crystals.

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