In primary hyperparathyroidism, the classic laboratory triad includes which combination?

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Multiple Choice

In primary hyperparathyroidism, the classic laboratory triad includes which combination?

Explanation:
The main idea is that in primary hyperparathyroidism the parathyroid glands produce too much PTH. This hormone raises serum calcium through bone resorption, increased renal calcium reabsorption, and more vitamin D activation (which boosts intestinal calcium absorption). At the same time PTH lowers serum phosphate by reducing its reabsorption in the kidneys, causing phosphate to be excreted. So the typical lab pattern is high calcium, elevated PTH, and low phosphate. This combination fits the physiology of an overactive parathyroid gland.

The main idea is that in primary hyperparathyroidism the parathyroid glands produce too much PTH. This hormone raises serum calcium through bone resorption, increased renal calcium reabsorption, and more vitamin D activation (which boosts intestinal calcium absorption). At the same time PTH lowers serum phosphate by reducing its reabsorption in the kidneys, causing phosphate to be excreted. So the typical lab pattern is high calcium, elevated PTH, and low phosphate. This combination fits the physiology of an overactive parathyroid gland.

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