In the management of rhabdomyolysis, which adjunct therapy is used to promote urine alkalinization?

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Multiple Choice

In the management of rhabdomyolysis, which adjunct therapy is used to promote urine alkalinization?

Explanation:
Rhabdomyolysis can injure the kidneys when myoglobin from damaged muscle precipitates in the tubules. Making the urine more alkaline helps keep myoglobin soluble and reduces tubular precipitation, lowering the risk of pigment nephropathy. The way to achieve this is with intravenous bicarbonate, which raises urine pH and promotes a safer tubular environment. Other options may aid hydration or diuresis but do not alkalinize the urine in the same targeted way. Monitor for fluid balance and electrolyte shifts, and avoid excessive alkalinization or volume overload.

Rhabdomyolysis can injure the kidneys when myoglobin from damaged muscle precipitates in the tubules. Making the urine more alkaline helps keep myoglobin soluble and reduces tubular precipitation, lowering the risk of pigment nephropathy. The way to achieve this is with intravenous bicarbonate, which raises urine pH and promotes a safer tubular environment. Other options may aid hydration or diuresis but do not alkalinize the urine in the same targeted way. Monitor for fluid balance and electrolyte shifts, and avoid excessive alkalinization or volume overload.

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