Melanoma originates from which type of pigment-producing cells?

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Study for the PANCE Precision Exam. Improve with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Melanoma originates from which type of pigment-producing cells?

Explanation:
Melanoma comes from melanocytes, the pigment-producing cells in the epidermis. Melanocytes reside in the basal layer of the epidermis and generate melanin in melanosomes, which are then transferred to surrounding keratinocytes to give skin its color and help protect against UV damage. When these pigment-producing melanocytes undergo malignant transformation, melanoma develops. Keratinocytes are the main epidermal cells that produce keratin, not pigment. Langerhans cells are immune cells in the epidermis, and fibroblasts are in the dermis making connective tissue—neither are pigment producers.

Melanoma comes from melanocytes, the pigment-producing cells in the epidermis. Melanocytes reside in the basal layer of the epidermis and generate melanin in melanosomes, which are then transferred to surrounding keratinocytes to give skin its color and help protect against UV damage. When these pigment-producing melanocytes undergo malignant transformation, melanoma develops.

Keratinocytes are the main epidermal cells that produce keratin, not pigment. Langerhans cells are immune cells in the epidermis, and fibroblasts are in the dermis making connective tissue—neither are pigment producers.

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