Pretibial myxedema is associated with which thyroid condition?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the PANCE Precision Exam. Improve with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Pretibial myxedema is associated with which thyroid condition?

Explanation:
Pretibial myxedema is a skin manifestation tied to Graves disease, driven by autoimmune TSH receptor antibodies that stimulate dermal fibroblasts to produce excess glycosaminoglycans. The resulting mucin deposition thickens the skin on the shins, producing waxy, non-pitting edema and induration. This extrathyroidal finding often accompanies other Graves features like hyperthyroidism and eye involvement, and it signals active autoimmune thyroid disease. The other conditions listed don’t share this specific pathophysiology or typical association with Graves disease.

Pretibial myxedema is a skin manifestation tied to Graves disease, driven by autoimmune TSH receptor antibodies that stimulate dermal fibroblasts to produce excess glycosaminoglycans. The resulting mucin deposition thickens the skin on the shins, producing waxy, non-pitting edema and induration. This extrathyroidal finding often accompanies other Graves features like hyperthyroidism and eye involvement, and it signals active autoimmune thyroid disease. The other conditions listed don’t share this specific pathophysiology or typical association with Graves disease.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy