The most common form of primary hyperaldosteronism is idiopathic bilateral adrenal hyperplasia, representing about what percentage?

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Multiple Choice

The most common form of primary hyperaldosteronism is idiopathic bilateral adrenal hyperplasia, representing about what percentage?

Explanation:
In primary hyperaldosteronism, the two main causes are bilateral adrenal hyperplasia (idiopathic) and a unilateral aldosterone-producing adenoma. Bilateral adrenal hyperplasia is more common because both glands enlarge and overproduce aldosterone rather than a single gland forming a focal tumor. This diffuse nature accounts for about six in ten cases, roughly 60%. Clinically, this distinction matters for treatment: bilateral disease is usually managed with mineralocorticoid receptor antagonists, while a unilateral adenoma can sometimes be cured with surgical removal.

In primary hyperaldosteronism, the two main causes are bilateral adrenal hyperplasia (idiopathic) and a unilateral aldosterone-producing adenoma. Bilateral adrenal hyperplasia is more common because both glands enlarge and overproduce aldosterone rather than a single gland forming a focal tumor. This diffuse nature accounts for about six in ten cases, roughly 60%. Clinically, this distinction matters for treatment: bilateral disease is usually managed with mineralocorticoid receptor antagonists, while a unilateral adenoma can sometimes be cured with surgical removal.

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