What is a common treatment for Oral Lichen Planus?

• A. Topical antibiotics
• B. Antivirals
• C. Sequestering therapy
• D. Local or systemic corticosteroids

Answer: (D)

Oral lichen planus is an immune-mediated inflammatory condition of the oral mucosa, so treatment focuses on dampening the immune response and reducing inflammation to relieve symptoms. Local or systemic corticosteroids are the most common choice because they suppress the T-cell–driven inflammation that drives the mucosal lesions, often leading to meaningful symptom relief and control of the disease.

For mild to moderate disease, topical corticosteroids (like a potent steroid applied to the lesions) are typically used first. If the disease is widespread, particularly with painful erosions, or if topical therapy isn’t enough, systemic corticosteroids may be prescribed to achieve broader anti-inflammatory effects. It’s important to monitor for side effects, such as oral candidiasis, and to use antifungal rinses as needed.

Antibiotics or antivirals aren’t standard treatments for oral lichen planus since it isn’t an infection-driven condition, and sequestration therapy isn’t a recognized approach for this disorder.