Which feature is typical of acromegaly?

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Multiple Choice

Which feature is typical of acromegaly?

Explanation:
Excess growth hormone after the growth plates have closed leads to acromegaly, a condition where soft tissues and bones gradually overgrow. The hallmark signs are enlargement of the hands and feet and coarsened facial features (such as a protruding jaw and brow), reflecting GH-driven tissue growth. This occurs via increased IGF-1 activity, promoting collagen and cell proliferation in connective tissues. Hypertension and hyperglycemia can accompany acromegaly due to insulin resistance, but weight loss or hypotension are not typical, and a trunk rash isn’t a feature. So the enlarged hands and facial features best illustrate acromegaly.

Excess growth hormone after the growth plates have closed leads to acromegaly, a condition where soft tissues and bones gradually overgrow. The hallmark signs are enlargement of the hands and feet and coarsened facial features (such as a protruding jaw and brow), reflecting GH-driven tissue growth. This occurs via increased IGF-1 activity, promoting collagen and cell proliferation in connective tissues. Hypertension and hyperglycemia can accompany acromegaly due to insulin resistance, but weight loss or hypotension are not typical, and a trunk rash isn’t a feature. So the enlarged hands and facial features best illustrate acromegaly.

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