Which laboratory findings support Kawasaki disease diagnosis?

• A. Low WBC and platelets with high calcium
• B. Normal WBC and platelets with normal ESR/CRP
• C. Elevated WBC and platelets with anemia and elevated ESR/CRP
• D. Elevated liver enzymes only

Answer: (D)

Kawasaki disease is diagnosed mainly on clinical criteria, with laboratory tests providing supportive but non-specific evidence of inflammation. In this condition you often see leukocytosis with neutrophilia, elevated inflammatory markers such as ESR and CRP, and thrombocytosis that tends to appear in the subacute phase. There can also be mild anemia and sometimes mild elevations in liver enzymes, but no single lab finding confirms the diagnosis.

Therefore, a lab pattern that includes elevated white blood cells and platelets along with anemia and elevated ESR/CRP fits the inflammatory picture of Kawasaki disease best. An isolated elevation in liver enzymes, by itself, is not specific or sufficient to support the diagnosis.