Which statement about secretory diarrhea is true?

• A. Secretory has no fever
• B. It has fever typically
• C. Abdominal tenderness focal
• D. Blood in stool common

Answer: (A)

Secretory diarrhea occurs when toxins or secretagogues stimulate active secretion of water and electrolytes into the intestinal lumen, producing large-volume watery stools that continue even with fasting. Because this form of diarrhea is not driven by mucosal inflammation, fever is not typical. The stool usually lacks inflammatory cells and blood, and abdominal tenderness is not a defining feature in secretory types. Fever and blood in the stool point more toward inflammatory or invasive infectious processes. So the statement that secretory diarrhea has no fever best fits, with examples like cholera where watery stools occur without fever.