Which statement best defines evidence-based medicine?

• A. Relying solely on randomized trials
• B. Using the best available evidence from research plus clinical expertise and patient values
• C. Following tradition and expert opinions
• D. Making decisions with personal experience only

Answer: (B)

Evidence-based medicine means making decisions by combining the best available research evidence with clinical expertise and the patient’s values and preferences. This approach uses high-quality evidence but also interprets it in the context of the individual patient and what matters to them, rather than relying solely on trials, tradition, or personal experience. The statement that mixes research evidence with clinical expertise and patient values best captures how EBM guides care. Solely relying on randomized trials can miss real-world applicability and patient priorities; following tradition or expert opinion depends more on authority than on evidence; and making decisions from personal experience alone ignores external data that could improve outcomes. In practice, you weigh the evidence, apply your clinical judgment, and align decisions with the patient’s goals through shared decision-making.